Are two neurons of the same type identical in how they fire, and which genes set the potassium channels behind it? · Lobeworks/17

No.

Are two neurons of the same type identical in how they fire, and which genes set the potassium channels behind it?

No. Cell identity sets most of the channel mix through gene families (KCNA for Kv1, KCNB for Kv2, KCNC for Kv3, KCNQ for Kv7, KCNMA1 for the BK channel), but two cells of a type differ in channel numbers, in where the channels sit on soma, dendrites and axon, in phosphorylation, age and history. Neurons also retune their own channels to keep their activity in range, which is homeostatic plasticity of excitability, so firing patterns drift with what a cell has been doing.