Why are oxytocin and vasopressin said to come from the pituitary when the hypothalamus makes them? · Grey Matter

Both hormones are made in the cell bodies of large neurons in the supraoptic and paraventricular nuclei of the hypothalamus.


Why are oxytocin and vasopressin said to come from the pituitary when the hypothalamus makes them?

Both hormones are made in the cell bodies of large neurons in the supraoptic and paraventricular nuclei of the hypothalamus. The neurons pack them into vesicles that travel down their axons, through the pituitary stalk, to endings in the posterior pituitary, where they are stored. When the neurons fire, the endings release the hormones into the capillaries of the posterior pituitary, so the gland is the place of release and the hypothalamus is the place of manufacture.